The concept of endogenous development assumes the use of specifi c resources of the region, difficult to copy, to its development, and even to gain a competitive advantage in a wider dimension. This concept has been used in the provisions of the Regional Innovation Strategy of the Podkarpackie Voivodeship for 2014-2020 for smart specialization (RIS3), especially in relation to leading smart specialization the quality of life, in the areas of: production and processing of ecological, regional and traditional food; renewable energy and distributed energy; agrotourism and ecotourism. It was targeted at the development of the entire region, not only the leading urban centers. The special role of the food economy lies in the need to guarantee food security and food sovereignty in the region. This issue is of strategic importance.