One of the current challenges in transport is e-mobility, understood as electromobility, ecomobility and mobility economics. E-mobility is nowadays a key focus area of socio-technical change, in terms of attention from policy makers as well as from industry and the public. The societal challenges ahead, in particular climate change put increasing pressure on the current mobility system, due to its tremendous environmental impact. Furthermore e-mobility is seen as major economic opportunity for the automotive industry. In this context, based on the available literature and documents and practical solutions implemented already in cities and agglomerations, the paper discusses the fundamental challenges that cities are to face in the context of the current megatrends. This process will engage diff erent stakeholders in order to make this concept become a reality.